发明名称 |
Alpha 1-Antitrypsin Compositions and Treatment Methods Using Such Compositions |
摘要 |
Alpha 1-antitrypsin compositions and treatment methods using such compositions for treating a variety of pulmonary diseases are provided. The compositions generally contain AAT, a stabilizing carbohydrate such as trehalose, a surfactant such as Polysorbate 80 and an antioxidant to stabilize AAT for use as a therapeutic. The formulations can be prepared as both liquids and solids and administered by nebulization of the liquid formulation or by conversion of dry powder formulation into an aerosol.
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申请公布号 |
US2010286066(A1) |
申请公布日期 |
2010.11.11 |
申请号 |
US20100714432 |
申请日期 |
2010.02.26 |
申请人 |
DURRANI MANZER;KUMAR HARISH;KRIEGER TIMOTHY;KABINGUE KEN;MOSHER VIRGINIA;BARR PHILIP J;BATHURST IAN C |
发明人 |
DURRANI MANZER;KUMAR HARISH;KRIEGER TIMOTHY;KABINGUE KEN;MOSHER VIRGINIA;BARR PHILIP J.;BATHURST IAN C. |
分类号 |
A61K38/14;A61K9/00;A61K9/19;A61K38/02;A61K38/57;A61K47/36;A61P11/00;C07K14/81 |
主分类号 |
A61K38/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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