发明名称 (Arylamidoaryl)squaramide compounds
摘要 Compounds represented by Formula (I): or a pharmaceutically acceptable salt or N-oxide thereof, wherein A, Q, Y, R5, m and J are defined herein, are useful in the treatment of tumors and cancers such as mastocytosis/mast cell leukemia, gastrointestinal stromal tumors (GIST), germ cell tumors, small cell lung carcinoma (SCLC), sinonasal natural killer/T-cell lymphoma, testicular cancer (seminoma), thyroid carcinoma, malignant melanoma, ovarian carcinoma, adenoid cystic carcinoma, acute myelogenous leukemia (AML), breast carcinoma, pediatric T-cell acute lymphoblastic leukemia, neuroblastoma, mast cell leukemia, angiosarcoma, anaplastic large cell lymphoma, endometrial carcinoma, and prostate carcinoma.
申请公布号 US7829717(B2) 申请公布日期 2010.11.09
申请号 US20050227699 申请日期 2005.09.15
申请人 OSI PHARMACEUTICALS, INC. 发明人 CASTELHANO ARLINDO L.;CREW ANDREW;DONG HANQING;LI AN-HU;QIU LI;SMITH ALUN;TARDIBONO LAWRENCE;ZHANG TAO
分类号 C07D215/12;A61K31/47 主分类号 C07D215/12
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