发明名称 |
2-heterosubstituted 3-aryl-4H-1-benzopyran-4-ones as novel therapeutics in breast cancer |
摘要 |
The present invention provides 2-heterosubstituted 3-aryl-4H-benzopyran-4-one compounds for the treatment of cancers, namely breast cancer. This invention further provides a method of synthesis of 2-(alkylthio)isoflavones that can be carried out at ambient conditions. This invention further provides a method of synthesis of the 2-heterosubstituted 3-aryl-4H-benzopyran-4-one from a 2-(alkylthio)isoflavone. The invention further provides methods of using the 2-heterosubstituted 3-aryl-4H-benzopyran-4-one compounds for the treatment of breast cancer in mammals.
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申请公布号 |
US7829557(B2) |
申请公布日期 |
2010.11.09 |
申请号 |
US20060511192 |
申请日期 |
2006.08.28 |
申请人 |
THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION |
发明人 |
BRUEGGEMEIER ROBERT W.;KIM YOUNG-WOO |
分类号 |
A61K31/5377;C07D311/56;C07D413/02 |
主分类号 |
A61K31/5377 |
代理机构 |
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地址 |
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