发明名称 |
INHIBITORS OF SEPARASE, METHOD FOR IDENTIFYING THEM AND USES |
摘要 |
Method for identifying compounds that interfere with or modulate sister chromatid separation in animal or plant cells by modulating a protease with separin-like cysteine endopeptidase activity. Inhibitors of separin activity are useful in cancer therapy, to prevent birth defects and to increase ploidy in plants.
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申请公布号 |
CA2362794(C) |
申请公布日期 |
2010.11.09 |
申请号 |
CA20002362794 |
申请日期 |
2000.02.14 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL GMBH |
发明人 |
UHLMANN, FRANK;NASMYTH, KIM;PETERS, JAN-MICHAEL;WAIZENEGGER, IRENE;BUONOMO, SARA;CLYNE, ROSEMARY |
分类号 |
A61K38/55;C12N15/09;A01H5/00;A61K45/00;A61P5/24;A61P35/00;A61P43/00;C07K14/39;C12N5/04;C12N9/99;C12Q1/00;C12Q1/37 |
主分类号 |
A61K38/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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