发明名称 |
Drug conjugates and their use for treating cancer, an autoimmune disease or an infectious disease |
摘要 |
Drug-Linker-Ligand Conjugates are disclosed in which a Drug is linked to a Ligand via a peptide-based Linker unit. In one embodiment, the Ligand is an Antibody. Drug-Linker compounds and Drug compounds are also disclosed. Methods for treating cancer, an autoimmune disease or an infectious disease using the compounds and compositions of the invention are also disclosed.
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申请公布号 |
US7829531(B2) |
申请公布日期 |
2010.11.09 |
申请号 |
US20090408646 |
申请日期 |
2009.03.20 |
申请人 |
SEATTLE GENETICS INC. |
发明人 |
SENTER PETER D.;DORONINA SVETLANA O.;TOKI BRIAN E. |
分类号 |
A61K38/00;A61K47/48;A61P35/00;C12P21/08 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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