摘要 |
Dendritic polymer conjugates which are composed of at least one dendrimer in association with at least one unit of a carried material, where the carrier material can be a biological response modifier, have been prepared. The conjugate can also have a target director present, and when it is present, then the carried material may be a bioactive agent. Preferred dendritic polymers are dense starr polymers, which have been complexed with biological response modifiers. These conjugates and complexes have particularly advantageous properties due to their unique characteristics.
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申请人 |
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发明人 |
WILSON, LARRY R.;YIN, RUI;TOMALIA, DONALD A.;BAKER, JAMES R.;BIELINSKA, ANNA U.;BROTHERS, HERBERT M., II;CHENG, ROBERTA C.;FAZIO, MICHAEL J.;HEDSTRAND, DAVID M.;JOHNSON, JENNIFER A.;KAPLAN, DONALD A.;KLAKAMP, SCOTT L.;KRUPER, WILLIAM J., JR.;KUKOWSKA-LATALLO, JOLANTA;MAXON, BARTLEY D.;PIEHLER, LARS T.;TOMLINSON, IAN A. |