发明名称 |
DETECTION OF NUCLEIC ACID SEQUENCE DIFFERENCES BY COMPARATIVE GENOMIC HYBRIDIZATION |
摘要 |
The present invention provides a method of detecting nucleotide sequence differences between two nucleic acid samples. The method employs a comparative genomic hybridization (CGH) technique to analyze the sequence differences between the samples. This method permits the identification of small sequence differences (e.g., sequence divergence of 1% or less) in nucleic acid samples of high complexity (e.g., an entire genome).
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申请公布号 |
US2010279876(A1) |
申请公布日期 |
2010.11.04 |
申请号 |
US20090405867 |
申请日期 |
2009.03.17 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
ALBERTSON DONNA G.;PINKEL DANIEL;FRIDYLAND JANE;HUEY BING;SNIJDERS ANTOINE;GRAY JOE W.;KALLIONIEMI ANNE;KALLIONIEMI OLLI-PEKKA;WALDMAN FREDERIC |
分类号 |
C40B30/00;C12Q1/68 |
主分类号 |
C40B30/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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