摘要 |
Crystal forms of (3R,4S)-7-hydroxymethyl-2,2,9-trimethyl-4-(phenethylamino)-3,4-dihydro-2H-pyrano[2,3-g]qunolin-3-ol, which is an excellent medicine, and processes for producing the crystal forms. The processes comprise crystallizing (3R,4S)-7-hydroxymethyl-2,2,9-trimethyl-4-(phenethylamino)-3,4-dihydro-2H-pyrano[2,3-g]qunolin-3-ol from an acetic acid ester solvent, an aliphatic hydrocarbon solvent, a nitrile solvent, an aromatic hydrocarbon solvent, a ketone solvent, or an ether solvent. The crystal forms are obtained by the processes. |
申请人 |
NISSAN CHEMICAL INDUSTRIES, LTD.;TAKADA, YASUTAKA;KAMON, MIYAKO;KAWAHARA, SHIRO;UMEDA, YASUHIRO |
发明人 |
TAKADA, YASUTAKA;KAMON, MIYAKO;KAWAHARA, SHIRO;UMEDA, YASUHIRO |