发明名称 |
METHOD FOR MOLECULAR BIOLOGY APPLICATIONS |
摘要 |
The invention provides a method of nucleic acid synthesis and/or amplification, and/or of improving the efficiency, activity and/or stability of at least one nucleic acid-modifying enzyme, comprising carrying out the method in the presence of (a) at least one organic-based macromolecule having a molecular weight of 50 kDa to 500 kDa and neutral surface charge; or (b) at least one organic-based macromolecule of radius 2 to 50 nm and neutral surface charge. There is also provided a method of determining the optimum crowding conditions of macromolecule(s) in solution.
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申请公布号 |
US2010279283(A1) |
申请公布日期 |
2010.11.04 |
申请号 |
US20070376926 |
申请日期 |
2007.08.10 |
申请人 |
RAGHUNATH MICHAEL;LAREU RICARDO RODOLFO;HARVE SUBRAMHANYA KARTHIK |
发明人 |
RAGHUNATH MICHAEL;LAREU RICARDO RODOLFO;HARVE SUBRAMHANYA KARTHIK |
分类号 |
C12Q1/68;C12N9/00;C12P19/34 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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