发明名称 PRODUCTION METHOD OF 6-HALOGENO-3-ARYLPYRIDINE DERIVATIVE
摘要 [Problem] The present invention provides an industrially advantageous production method of a 6-halogeno-3-arylpyridine derivative in which cryogenic condition is not required, production step is short, and an isomer difficult to be separated is not produced as a by-product, [Solution] A production method of a 6-halogeno-3-arylpyridine derivative represented by the general formula (III) comprising: the first step reacting a 2,5-dihalogenopyridine derivative represented by the general formula (I) with a magnesiation reagent; and the second step reacting the product obtained from the above-described first step, in the presence of a palladium compound, with a halogenoaryl derivative represented by the general formula (II).
申请公布号 US2010280253(A1) 申请公布日期 2010.11.04
申请号 US20080809868 申请日期 2008.12.19
申请人 KURARAY CO., LTD. 发明人 KASHIKI NOBUSUKE;MORI TOSHIKI;UJITA KATSUJI
分类号 C07D213/61 主分类号 C07D213/61
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