发明名称 |
ANTI-IL-3R? ANTIBODY FOR USE IN TREATMENT OF BLOOD TUMOR |
摘要 |
Disclosed are: an antibody against a human IL-3Ra chain, which does not inhibit an IL-3 signal, can bind to a B domain of the human IL-3Ra chain, and cannot bind to a C domain of the human IL-3Ra chain; a composition for preventing or treating a blood tumor in which IL-3Ra-expressing cells are observed in a bone marrow or a peripheral blood in a subject, which is characterized by comprising the human IL-3Ra antibody as an active ingredient; and a method for treating a blood tumor in which IL-3Ra-expressing cells are observed in a bone marrow or a peripheral blood, which is characterized by administering a composition containing the human IL-3Ra antibody as an active ingredient to a subject. |
申请公布号 |
WO2010126066(A1) |
申请公布日期 |
2010.11.04 |
申请号 |
WO2010JP57510 |
申请日期 |
2010.04.27 |
申请人 |
KYOWA HAKKO KIRIN CO., LTD.;TAWARA, TOMONORI;TAKAYANAGI, SHINICHIRO;INAGAKI, YOSHIMASA |
发明人 |
TAWARA, TOMONORI;TAKAYANAGI, SHINICHIRO;INAGAKI, YOSHIMASA |
分类号 |
C07K16/28;A61K39/395;A61P35/02;C07K16/46;C12N15/02;C12N15/09;C12P21/08;C12R1/91;G01N33/53;G01N33/574;G01N33/577 |
主分类号 |
C07K16/28 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|