DUAL MECHANISM INHIBITORS FOR THE TREATMENT OF DISEASE
摘要
Provided are compounds that are inhibitors of both rho kinase and of a monoamine transporter (MAT) act to improve the disease state or condition. Further provided are compositions comprising the compounds. Further provided are methods for treating diseases or conditions, the methods comprising administering compounds according to the invention. One such disease may be glaucoma for which, among other beneficial effects, a marked reduction in intraocular pressure (lOP) may be achieved.
申请公布号
WO2010126626(A2)
申请公布日期
2010.11.04
申请号
WO2010US22246
申请日期
2010.01.27
申请人
AERIE PHARMACEUTICALS, INC.;DELONG, MITCHELL, A.;STURDIVANT, JILL, MARIE;ROYALTY, SUSAN, M.
发明人
DELONG, MITCHELL, A.;STURDIVANT, JILL, MARIE;ROYALTY, SUSAN, M.