发明名称 CO-PROCESSED EXCIPIENT COMPOSITIONS
摘要 <p>An oral solid dosage form having improved dissolution profile and a method of producing the same are provided. The present invention particularly provides a co-processed excipient composition and a method of producing the same. More particularly, it relates to a co-processed binary mixture of crosslinked polyvinylpyrrolidone and calcium silicate; wherein the weight ratio of crosslinked polyvinylpyrrolidone and calcium silicate is in the range of 1 : 1 to 20: 1. The binary mixture when combined with a poorly soluble drug enhances its dissolution and extent of release.</p>
申请公布号 WO2010126828(A1) 申请公布日期 2010.11.04
申请号 WO2010US32406 申请日期 2010.04.26
申请人 ISP INVESTMENTS INC.;UMESH, RAO, VINAY;BALASUBRAMANIAM, JAGDISH;KRISHNA, HALDAR, RAMA 发明人 UMESH, RAO, VINAY;BALASUBRAMANIAM, JAGDISH;KRISHNA, HALDAR, RAMA
分类号 A61K9/20 主分类号 A61K9/20
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