发明名称 |
Chimeric and humanized antibodies to alpha5beta1 integrin that modulate angiogenesis |
摘要 |
<p>The present invention provides chimeric and humanized antibodies that specifically recognize alpha5beta1 integrin, and methods for using the antibodies for reducing or inhibiting angiogenesis in a tissue. Also provided are methods of determining therapeutically acceptable doses of the antibodies and pharmaceutical compositions including the same.</p> |
申请公布号 |
AU2003298783(B2) |
申请公布日期 |
2010.11.04 |
申请号 |
AU20030298783 |
申请日期 |
2003.11.26 |
申请人 |
FACET BIOTECH CORPORATION |
发明人 |
URSULA JEFFRY;VANITHA RAMAKRISHNAN;DALE E. JOHNSON;DAVID POWERS |
分类号 |
C07K16/28;C07K16/42 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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