发明名称 CDK INHIBITOR SALTS
摘要 The present invention relates to novel crystalline form(s) of water-soluble salts and of free base of a cdk inhibitor. Such crystal salts are for example fumarate, L-malate, maleate, succinate, adipate, malonate, glycolate, phosphate, mesylate, L-lactate, hydrochloride, di-hydrochloride, tri-hydrochloride. Hydrates and polymorphs of such new salt forms, a process for their preparation, their utility in therapy and to the pharmaceutical compositions containing them are also claimed and described in the present application.
申请公布号 WO2010125004(A1) 申请公布日期 2010.11.04
申请号 WO2010EP55463 申请日期 2010.04.23
申请人 NERVIANO MEDICAL SCIENCES S.R.L.;ZAMPIERI, MASSIMO;AIROLDI, ANNALISA;FORNARETTO, MARIA GIOIA;BRASCA, MARIA GABRIELLA 发明人 ZAMPIERI, MASSIMO;AIROLDI, ANNALISA;FORNARETTO, MARIA GIOIA;BRASCA, MARIA GABRIELLA
分类号 C07D487/04;A61K31/33;A61P35/00 主分类号 C07D487/04
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