发明名称 |
METHOD OF INHIBITING CANCER CELL PROLIFERATION, PROLIFERATION INHIBITOR AND SCREENING METHOD |
摘要 |
The present invention provides a method of inhibiting cancer cell proliferation by suppressing a function of ZNF143, a cancer cell proliferation inhibitor containing as an active ingredient a substance capable of inhibiting a function of ZNF143, like a ZNF143-specific siRNA, a prophylactic and/or therapeutic drug for cancer, a method of detecting cancer cells, a diagnostic reagent for cancer, a vector and transformant cell incorporating the vector, and a screening method for a substance possessing cancer cell proliferation inhibitory activity with the amount of inhibition of the binding of ZNF143 protein as an index.
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申请公布号 |
EP2246069(A1) |
申请公布日期 |
2010.11.03 |
申请号 |
EP20080869206 |
申请日期 |
2008.12.26 |
申请人 |
UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH, JAPAN |
发明人 |
KOHNO, KIMITOSHI;IZUMI, HIROTO;SASAGURI, YASUYUKI |
分类号 |
A61K45/00;A61K31/7105;A61K31/713;A61K35/76;A61K48/00;A61P35/00;G01N33/15;G01N33/50;G01N33/53;G01N33/574 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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