发明名称 |
Cyclic urea compounds, preparation thereof and pharmaceutical use thereof as kinase inhibitors |
摘要 |
The disclosure relates to a cyclic urea compound of formula I: as defined herein, to the process for its preparation, pharmaceutical composition comprising it and its pharmaceutical use as an inhibitor on a protein kinase. Thus, the compound of formula I is useful for preventing or treating a physiological disorder capable of being modulated by inhibiting the activity of a protein kinase, such as a solid tumor.
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申请公布号 |
US7825115(B2) |
申请公布日期 |
2010.11.02 |
申请号 |
US20080972314 |
申请日期 |
2008.01.10 |
申请人 |
AVENTIS PHARMA S.A. |
发明人 |
PATEK MARCEL;NAIR ANIL;HITTINGER AUGUSTIN;NEMECEK CONCEPTION;BOND DANIEL;HARLOW GREG;BOUCHARD HERVE;MAUGER JACQUES;MALLERON JEAN-LUC;PALERMO MARK;AL-OBEIDI FAHAD;FAITG THOMAS;STROBEL HARTMUT;RUF SVEN;RITTER KURT;EL-AHMAD YOUSSEF;LESUISSE DOMINIQUE;BENARD DIDIER |
分类号 |
C07D401/06;A61K31/41;C07D401/14;C07D403/06 |
主分类号 |
C07D401/06 |
代理机构 |
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代理人 |
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地址 |
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