发明名称 |
PROCESS FOR LABELING A RIBONUCLEIC ACID, AND LABELED RNA FRAGMENTS WHICH ARE OBTAINED THEREBY |
摘要 |
The present invention relates to a process for labeling with signal amplification a ribonucleic acid (RNA), characterized in that it comprises: fragmenting the RNA, fixing a first ligand to the terminal phosphate which is located at the 3' end and/or the 5' end of each fragment of said RNA, said terminal phosphate having been released during the fragmentation, and binding a labeling agent to said first ligand. The invention is preferably applied in the field of medical diagnosis.
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申请公布号 |
CA2394392(C) |
申请公布日期 |
2010.11.02 |
申请号 |
CA19992394392 |
申请日期 |
1999.12.17 |
申请人 |
BIO MERIEUX;AFFYMETRIX INCORPORATED |
发明人 |
LAAYOUN, ALI;DO, DUC;MIYADA, CHARLES GARRET |
分类号 |
C12N15/09;C12Q1/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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