发明名称 |
Inhibition of FGFR3 and treatment of multiple myeloma |
摘要 |
Methods of inhibiting fibroblast growth factor receptor 3 and treating various conditions mediated by fibroblast growth factor receptor 3 are provided that include administering to a subject a compound of Structure I, a pharmaceutically acceptable salt thereof, a tautomer thereof, or a pharmaceutically acceptable salt of the tautomer. Compounds having the Structure I have the following structure where and have the variables described herein. Such compounds may be used to prepare medicaments for use in inhibiting fibroblast growth factor receptor 3 and for use in treating conditions mediated by fibroblast growth factor receptor 3 such as multiple myeloma.
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申请公布号 |
US7825132(B2) |
申请公布日期 |
2010.11.02 |
申请号 |
US20040983174 |
申请日期 |
2004.11.05 |
申请人 |
NOVARTIS VACCINES AND DIAGNOSTICS, INC. |
发明人 |
CAI SHAOPEI;CHOU JOYCE;HARWOOD ERIC;HEISE CARLA C.;MACHAJEWSKI TIMOTHY D.;RYCKMAN DAVID;SHANG XIAO;WIESMANN MARION;ZHU SHUGUANG |
分类号 |
A61K31/47;A01N43/40;A61K31/496 |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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地址 |
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