发明名称 Clustered multi-antigenic carbohydrate constructs, methods for their preparation, and uses thereof
摘要 The present invention provides novel clustered multi-antigenic constructs having the structure: and methods for the synthesis thereof. In still another aspect, the present invention provides methods for the treatment of cancer, preferably for the prevention of recurrence of cancer, and methods for inducing antibodies in a subject, comprising administering to a subject in need, an effective amount of any of the inventive constructs as disclosed herein, either in conjugated form or unconjugated and in combination with a suitable immunogenic carrier.
申请公布号 US7824687(B2) 申请公布日期 2010.11.02
申请号 US20030728041 申请日期 2003.12.03
申请人 SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH 发明人 DANISHEFSKY SAMUEL J.;KEDING STACY J.
分类号 A01N43/04;A61K31/70;A61K31/715;A61K38/00;A61K38/14;A61K39/00;A61K39/385;A61K47/48;C07H15/04;C07H15/10;C07H15/18;C07K1/107;C07K4/00;C07K5/078;C07K9/00;C07K14/435;C08B37/00 主分类号 A01N43/04
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