NOVEL FETAL MARKERS FOR PRENATAL DIAGNOSIS AND MONITORING
摘要
This application provides the use of novel fetal markers for prenatal diagnosis and monitoring of certain pregnancy-related conditions. More specifically, the invention resides in the discovery that certain CpG islands located on fetal chromosome 21 demonstrate a methylation profile that is distinct from that of the corresponding CpG islands located on maternal chromosome 21. This application also provides kits for diagnosing or monitoring of the relevant conditions.
申请公布号
EA014274(B1)
申请公布日期
2010.10.29
申请号
EA20080002272
申请日期
2007.05.03
申请人
THE CHINESE UNIVERSITY OF HONG KONG
发明人
LO YUK, MING, DENNIS;CHIU ROSSA, WAI, KWUN;CHIM STEPHEN, SIU, CHUNG;DING CHUNMING;JIN SHENGNAN;LEE TRACY, YUEN, HAN;LUN FIONA, MIU, FUN