发明名称 SUBSTANTIALLY PURE HISTIDINE-LINKED PROTEIN POLYMER CONJUGATES
摘要 <p>Substantially pure histidine-linked protein-polymer conjugates and processes for their preparation are disclosed. The processes include contacting a protein with an activated polymer under conditions sufficient to facilitate covalent attachment of at least a portion of the polymer strands on histidine residues of the protein and thereafter substantially separating the histidine-linked conjugates from the remaining reactants. NO SUITABLE FIGURE</p>
申请公布号 SG165132(A1) 申请公布日期 2010.10.28
申请号 SG19980005819 申请日期 1998.12.14
申请人 ENZON, INC. 发明人 LEE SEOJU;MCNEMAR CHARLES
分类号 A61K47/34;A61K38/00;A61K38/21;A61K38/22;A61K47/48;C07K1/113;C07K14/54;C07K14/56;C07K14/565;C07K17/08;(IPC1-7):C07K1/08;A61K38/20 主分类号 A61K47/34
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