发明名称 ISOFLAVONE METABOLITES
摘要 There are disclosed compounds of formulae (I) or (II) in which A is selected from the group consisting of (1), (2), (3) and (4); OH, and one of R1 and R2 is selected from H, OH and OCH3, and the other of R1 and R2 is selected from OH and OCH3; one of R3 and R4 is selected from H, OH and OCH3, and the other of R3 and R4 is selected from OH and OCH3; provided that at least one of the pairs R1, R2 and R3, R4 are both OH; R5 is selected from OH and OCH3; and denotes a single or double bond; and pharmaceutically acceptable salts and prodrugs thereof. The compounds of the invention are useful for the treatment of hormone-dependent conditions and cancers.
申请公布号 US2010273891(A1) 申请公布日期 2010.10.28
申请号 US20100833042 申请日期 2010.07.09
申请人 JOANNOU GEORGE EUSTACE 发明人 JOANNOU GEORGE EUSTACE
分类号 A61K31/12;A23L1/30;A61K31/352;A61K31/353;A61P9/10;A61P9/12;A61P17/10;A61P17/14;A61P19/10;A61P25/06;A61P25/28;A61P29/00;A61P35/00;A61P39/06;C07C45/46;C07C45/62;C07C45/67;C07C45/75;C07C49/245;C07C49/248;C07C49/747;C07C49/83;C07C49/835;C07D311/36;C07D311/38;C07D311/58;C12N1/00 主分类号 A61K31/12
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