| 发明名称 |
DIACYLETHYLENEDIAMINE COMPOUND |
| 摘要 |
Disclosed is a compound useful as an anti-obesity agent. Studies have been made on compounds which have a DGAT1 inhibitory activity and are therefore promising active ingredients for pharmaceutical compositions for treating obesity, type-II diabetes, fatty liver and diseases associated with the aforementioned diseases, and it is confirmed that a specific diacylethylenediamine compound has an excellent DGAT1 inhibitory activity. The diacylethylenediamine compound has a DGAT1 inhibitory activity and can be used as a prophylactic and/or therapeutic agent for obesity, type-II diabetes, fatty liver and diseases associated with the aforementioned diseases.
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| 申请公布号 |
CA2759264(A1) |
申请公布日期 |
2010.10.28 |
| 申请号 |
CA20102759264 |
申请日期 |
2010.04.19 |
| 申请人 |
ASTELLAS PHARMA INC. |
发明人 |
KAWANO, TOMOAKI;YONETOKU, YASUHIRO;HANAZAWA, TAKESHI;NIGAWARA, TAKAHIRO;FUKUDOME, HIROKI;MORITANI, HIROSHI |
| 分类号 |
C07C235/46;A61K31/343;A61K31/351;A61K31/357;A61K31/36;A61K31/381;A61K31/40;A61K31/402;A61K31/4035;A61K31/404;A61K31/41;A61K31/415;A61K31/421;A61K31/4245;A61K31/425;A61K31/427;A61K31/428;A61K31/4365;A61K31/439;A61K31/44;A61K31/445;A61K31/451;A61K31/4535;A61K31/4545;A61K31/455;A61K31/47;A61K31/495;A61K31/4985;A61K31/505;A61K31/5375;A61P1/16;A61P3/04;A61P3/10;A61P43/00;C07C235/84;C07C237/34;C07C255/46;C07C275/26;C07C275/28;C07C307/06;C07C311/51;C07C317/44;C07C323/62;C07D207/06;C07D209/08;C07D209/42;C07D209/44;C07D211/16;C07D211/34;C07D211/44;C07D211/60;C07D213/81;C07D213/82;C07D215/48;C07D217/26;C07D231/22;C07D239/42;C07D241/04;C07D257/04;C07D263/32;C07D263/34;C07D263/48;C07D271/06;C07D271/10;C07D275/02;C07D277/20;C07D277/56;C07D277/68;C07D295/14;C07D295/18;C07D295/20;C07D307/79;C07D309/06;C07D317/46;C07D319/18;C07D333/38;C07D333/54;C07D333/68;C07D333/70;C07D451/02;C07D495/04 |
主分类号 |
C07C235/46 |
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