发明名称 |
Viable non-toxic gram-negative bacteria |
摘要 |
The present invention provides non-toxic Gram-negative bacteria. In particular, the present invention provides viable Gram-negative bacteria (e.g., E. coli) substantially lacking lipopolysaccharide (LPS, endotoxin) within the outer membrane. The present invention further provides methods of generating viable non-toxic Gram-negative bacteria and uses thereof. The present invention also provides compositions and methods for inducing immune responses and for researching and developing therapeutic agents.
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申请公布号 |
US2010272758(A1) |
申请公布日期 |
2010.10.28 |
申请号 |
US20070655413 |
申请日期 |
2007.01.19 |
申请人 |
REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
WOODARD RONALD WESLEY;MEREDITH TIMOTHY CHARLES;AGGARWAL PARAG |
分类号 |
A61K39/095;A61K39/02;A61K39/10;A61K39/102;A61K39/104;A61K39/106;A61K39/108;A61K39/112;A61K39/118;A61P1/12;A61P31/00;C12N1/00;C12N1/20;C12N1/21;C12P7/64;C12Q1/18 |
主分类号 |
A61K39/095 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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