| 发明名称 |
Optimized Antibodies that Target CD19 |
| 摘要 |
Antibodies that target CD19, wherein the antibodies comprise at least one modification relative to a parent antibody, wherein the modification alters affinity to an FcyR or alters effector function as compared to the parent antibody, and methods of using the antibodies. |
| 申请公布号 |
US2010272723(A1) |
申请公布日期 |
2010.10.28 |
| 申请号 |
US20070377251 |
申请日期 |
2007.08.14 |
| 申请人 |
XENCOR, INC. |
发明人 |
BERNETT MATTHEW J.;CHU SEUNG YUP;DESJARLAIS JOHN R.;KARKI SHER BAHADUR;LAZAR GREGORY ALAN;PONG ERIK WEIKING;RICHARDS JOHN O.;ZHUKOVSKY EUGENE ALEXANDER |
| 分类号 |
A61K39/395;A61P19/02;A61P35/00;A61P35/02;A61P37/00;C07H21/00;C07K16/28 |
主分类号 |
A61K39/395 |
| 代理机构 |
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