发明名称 2-ALKYL PIPERIDINE MGLUR5 RECEPTOR MODULATORS
摘要 <p>The present invention is directed to 2-alkylpiperidines which are positive allosteric modulators of metabotropic glutamate receptors, particularly the mGluR5 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.</p>
申请公布号 WO2010124055(A1) 申请公布日期 2010.10.28
申请号 WO2010US32001 申请日期 2010.04.22
申请人 MERCK SHARP & DOHME CORP.;MERCER, SWATI, P.;ROECKER, ANTHONY, J.;WILLIAMS, THERESA;ZHANG, XU-FANG 发明人 MERCER, SWATI, P.;ROECKER, ANTHONY, J.;WILLIAMS, THERESA;ZHANG, XU-FANG
分类号 A01N43/82;A61K31/41 主分类号 A01N43/82
代理机构 代理人
主权项
地址