发明名称 |
PULMONARY DELIVERY PARTICLES COMPRISING WATER INSOLUBLE OR CRYSTALLINE ACTIVE AGENTS |
摘要 |
A pulmonary delivery medicament comprises a plurality of particulates, the particulates comprising a structural matrix and a water insoluble and/or crystalline active agent. The particulates have a geometric diameter of 0.5 to 50 μm. The water insoluble active agent can be a fungicide, antibiotic, budesonide. A method of making the medicament comprises forming a liquid feedstock, and forming a feedstock suspension by suspending in the liquid feedstock, the active agent and an excipient capable of forming a structural matrix, such as a phospholipid. The feedstock suspension is spray dried to produce the particulates.
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申请公布号 |
US2010272823(A1) |
申请公布日期 |
2010.10.28 |
申请号 |
US20100774540 |
申请日期 |
2010.05.05 |
申请人 |
TARARA THOMAS E;WEERS JEFFREY G;KABALNOV ALEXEY;SCHUTT ERNEST G;DELLAMARY LUIS A |
发明人 |
TARARA THOMAS E.;WEERS JEFFREY G.;KABALNOV ALEXEY;SCHUTT ERNEST G.;DELLAMARY LUIS A. |
分类号 |
A61K9/00;A61K9/14;A61K9/12;A61K9/16;A61K9/22;A61K9/51;A61K9/72;A61K31/56;A61K31/7088;A61K31/713;A61K38/00;A61K38/43;A61K45/00;A61K47/24;A61K49/04;A61P9/00;A61P11/00;A61P23/00;A61P29/00;A61P31/00;A61P37/08;A61P39/00;B29B9/12 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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地址 |
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