CHIMERIC NEWCASTLE DISEASE VIRUSES AND USES THEREOF
摘要
Described herein are chimeric Newcastle disease viruses engineered to express a heterologous interferon antagonist and compositions comprising such viruses. The chimeric Newcastle disease viruses and compositions are useful in the treatment of cancer.
申请公布号
WO2010091262(A8)
申请公布日期
2010.10.28
申请号
WO2010US23335
申请日期
2010.02.05
申请人
MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY;MEMORIAL SLOAN-KETTERING CANCER CENTER;ZAMARIN, DMITRIY;GARCIA-SASTRE, ADOLFO;PALESE, PETER;FONG, YUMAN