发明名称 |
RGD-MODIFIED ALGINATE MICROPARTICLES AS A DRUG RELEASE SYSTEM |
摘要 |
The object of the present invention is to provide particles of a polymeric material containing cells therein, wherein said particles have a strength that is substantially greater than the microcapsules known in the state of the art. Said strength is achieved by means of functionalizing the polymeric material forming the microcapsule with a peptide which can bind to the adhesion proteins of the cell membrane, such that the cells act as cross-linking agents of the matrix resulting in an improvement of the mechanical properties of the matrixes |
申请公布号 |
US2010272812(A1) |
申请公布日期 |
2010.10.28 |
申请号 |
US20080666677 |
申请日期 |
2008.06.25 |
申请人 |
UNIVERSIDAD DEL PAIS VASCO |
发明人 |
ORIVE ARROYO GORKA;PEDRAZ MUNOZ JOSE LUIS;HERNANDEZ ROSA MARIA |
分类号 |
A61K9/14;A61K35/12;A61P7/06;A61P13/12;A61P15/00;A61P25/18;A61P25/28;B05D3/00;C12N11/02;C12N11/10 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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