PROCESS FOR THE PREPARATION OF DIALKYL 3-ALKOXYGLUTARATES

摘要

The invention relates to an one-step, continuous process for preparing a dialkyl 3- alkoxyglutarate of formula RO(CO)CH2C(OR)CH2(CO)OR, wherein R is C1-6 alkyl, by reacting 2 equivalents of ketene with 1 equivalent of an ortho formate of formula (RO)3CH, wherein R is as defined above, in the presence of an acidic catalyst.