| 摘要 |
The invention relates to compounds and compositions with antifungal activity, particularly against onychomycosis. Particularly, the invention is directed to use of fermented cereal grain for treatment of fungal infections, to composition with Lactobacillus species fermented cereal grain and a penetration enhancer, to an applicator comprising a brush, a reservoir, a cap, and a liquid composition comprising fermented cereal grain and preferably a penetration enhancer, to methods of treating onychomycosis by applying an antifungal composition comprising Lactobacillus species fermented rye, to compositions comprising ²-1,3-d-glucan and a penetration enhancer, to ²-1,3-d-glucan for use as a direct antifungal agent and to the use of ²-1,3-d-glucan for the manufacture of a medication for the treatment of onychomycosis. |
