摘要 |
PROBLEM TO BE SOLVED: To provide a method capable of efficiently producing an isoquinoline alkaloid useful as a drug using cocculaurine-N-methyl transferase(CNMT). SOLUTION: N-methyl cocculaurine and/or various kinds of alkaloids biosynthesized from the N-methyl cocculaurine are produced by using CNMT being N-methyl cocculaurine biosynthetic enzyme. |