Sulfonyl-quinoline derivatives

摘要

New mGluR1 and mGluR5 receptor subtype preferring ligands of formula: (I) and/or salts and/or hydrates and/or solvates thereof, to the processes and intermediates for their preparation, to pharmaceutical compositions containing these compounds and to their use in therapy and/or prevention of a condition which requires modulation of mGluR1 and mGluR5 receptors. FORMULE (I) wherein Arrepresents an optionally substituted phenyl or heteroaryl group; Arrepresents a substituted phenyl or an optionally substituted heteroaryl group; R, R, Rand Rrepresent independently a substituent selected from hydrogen, halogen, cyano, alkyl, alkoxy, hydroxy, trifluoromethyl, amino, alkylamino, dialkylamino, aminomethyl, alkylaminomethyl, dialkylaminomethyl.