发明名称 |
CULTURE METHOD FOR KERATINOCYTES AND USE THEREOF |
摘要 |
<p>Culture medium (A) comprises chicken serum and a culture substrate of inactivated fibroblasts. - Independent claims are also included for the following: - (1) keratinocyte culture that comprises (A); - (2) method for culturing epidermal cells and keratinocytes that comprises inoculating (A) with a suspension of keratinocytes then incubation; - (3) process for propagating a virus in vitro by culturing virus-infected keratinocytes by method (2) and extracting the virions formed; - (4) enveloped, live but attenuated DNA virions produced by method (3); and - (5) live, attenuated vaccines containing at least one virion of (4) and a vaccine carrier. - ACTIVITY - Virucide; Cytostatic. - No details of tests for these activities are given. - MECHANISM OF ACTION - Vaccine.</p> |
申请公布号 |
EP1649011(B1) |
申请公布日期 |
2010.10.27 |
申请号 |
EP20040767688 |
申请日期 |
2004.07.15 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) |
发明人 |
DJIAN, PHILIPPE;VANHOUTTEGHEM, AMANDINE, LAETITIA, VANESSA |
分类号 |
C12N5/071;A61K39/12;A61K39/255;A61K39/275;C12N7/00;C12N7/02 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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