This invention relates to methods for the generation of humanized antibodies, particularly a humanized antibody heavy chain protein and a humanized antibody light chain protein. The method comprises using cells that express or can be induced to express Activation Induced Cytidine Deaminase (AID).
申请公布号
EP2126087(A4)
申请公布日期
2010.10.27
申请号
EP20080725984
申请日期
2008.02.20
申请人
ANAPTYSBIO, INC.
发明人
HORLICK, ROBERT, A.;CUBITT, ANDREW, B.;BOWERS, PETER, M.