发明名称 Heteroaryl nitrile derivatives
摘要 The invention provides compounds of formula I or a pharmaceutically acceptable salt or ester thereof wherein the symbols have meaning as defined, which are inhibitors of cathepsin K and find use pharmaceutically for treatment of diseases and medical conditions in which cathepsin K is implicated, e.g. various disorders including inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis and tumors.
申请公布号 US7820818(B2) 申请公布日期 2010.10.26
申请号 US20090399761 申请日期 2009.03.06
申请人 NOVARTIS AG 发明人 ALTMANN EVA;BETSCHART CLAUDIA;HAYAKAWA KENJI;IRIE OSAMU;SAKAKI JUNICHI;IWASAKI GENJI;LATTMANN RENE;MISSBACH MARTIN;TENO NAOKI
分类号 C07D239/47;A61K31/505;A61K31/506;A61P19/02;C07D239/42;C07D239/48;C07D239/94;C07D401/06;C07D401/12;C07D401/14;C07D403/06;C07D403/10;C07D403/12;C07D413/12;C07D417/06;C07D473/34 主分类号 C07D239/47
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