发明名称 Crystalline polymorphs of desvenlafaxine succinate and their preparations
摘要 The present invention is directed to two new polymorph Form V and Form F of desvenlafaxine succinate, to processes of their preparations, pharmaceutical composition comprising such materials and their use in therapy. Form V is prepared from recrystallizing desvenlafaxine succinate in a mixture of tetrahydrofuran and ethanol. Form F is obtained from recrystallization of desvenlafaxine succinate in a mixture of cyclohexane and polar solvents such as ethanol, THF, methanol or isopropyl alcohol.
申请公布号 US7820716(B2) 申请公布日期 2010.10.26
申请号 US20070982622 申请日期 2007.11.05
申请人 MAI DE LTD 发明人 HUANG CAI GU;HUANG HUI MIN HE
分类号 A61K31/205;C07C55/10 主分类号 A61K31/205
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