SYNERGISTIC FILLER COMPOSITION OF PVP-VA AND SILICIFIED MYCROCRYSTALLINE CELLULOSE FOR TABLET DOSAGE FORM

摘要

A synergistic filler composition for making pharmaceutical tablets of sufficient tablet hardness at low compression force, and low friability, to preclude damage to the tablet upon further processing and without requiring a substantial increase in the size of the tablet, comprising (a) a PVP-VA copolymer and (b) a microcrystalline cellulose.