发明名称 |
Reduction of intravenously administered nanoparticulate-formulation-induced adverse physiological reactions |
摘要 |
Disclosed are methods of intravenous administration of nanoparticulate drug formulations to a mammal to avoid adverse hemodynamic effects: by reducing the rate and concentration of the nanoparticles in the formulations; or by pre-treating the subject with histamine; or by pretreating the subject with a desensitizing amount of the nanoparticulate drug formulations.
|
申请公布号 |
USRE41884(E1) |
申请公布日期 |
2010.10.26 |
申请号 |
US20080027100 |
申请日期 |
2008.02.06 |
申请人 |
ELAN PHARMA INTERNATIONAL LIMITED |
发明人 |
DE GARAVILLA LAWRENCE;LIVERSIDGE ELAINE;LIVERSIDGE GARY G. |
分类号 |
A61K9/16;A61K9/50;A61K9/127;A61K9/14;A61K45/06;A61K49/04;A61K49/18;B01J13/02;B32B5/16 |
主分类号 |
A61K9/16 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|