摘要 |
The invention relates to novel 2-substituted D-homo-estra-1,3,5(10)-trienes of general formula (I) wherein Rrepresents a C-Calkyl, a C-Calkyloxy group or a halogen atom, Rrepresents a hydrogen atom or a methyl group, and Rrepresents a hydrogen atom or a fluorine atom. The invention also relates to the pharmaceutically acceptable salts of said compounds, to the production thereof, and to the use of the same as medicaments for the prophylaxis and treatment of oestrogen-dependent diseases that can be influenced by the inhibition of 17β-hydroxy steroid dehydrogenase type 1. |