| 发明名称 |
TARGETING OPPOSITE STRAND REPLICATION INTERMEDIATES OF SINGLE-STRANDED VIRUSES BY RNAI |
| 摘要 |
The invention relates to methods and compositions for modulating viral replication through double-stranded RNA-mediated gene silencing (RNAi), wherein the antiviral methods and compositions preferentially target opposite strand replication intermediates of single-stranded RNA viruses.
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| 申请公布号 |
US2010267805(A1) |
申请公布日期 |
2010.10.21 |
| 申请号 |
US20100714949 |
申请日期 |
2010.03.01 |
| 申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
MCCALLUS DANIEL E.;PACHUK CATHERINE;GU BAOHUA |
| 分类号 |
A61K31/713;A61P31/12;C12N15/113 |
主分类号 |
A61K31/713 |
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