摘要 |
<p>A 3-aryl or heteroaryl-substituted indole derivative which is effective as a preventive or remedy for various diseases is provided. [Means for Resolution] A compound represented by a formula (I) or a pharmaceutically acceptable salt thereof is provided. In the formula, R1 represents a hydrogen atom, C1-6 alkyl et al; R2 represents a hydrogen atom, C1-6 alkyl et al; Z represents aryl or heteroaryl (with the proviso that imidazolyl is excluded); and W represents a group represented by the formula (w-1) or (w-2). In the formula, R3 represents C1-6 alkyl et al; Y1 and Y2 both represent a hydrogen atom or Y1 and Y2 together form -CH2-CH2-; Q represents CH or N; Ar represents phenyl, furyl et al; R4 and R5 each independently represent a hydrogen atom or C1-6 alkyl or R4 and R5 together with the nitrogen atom form pyrrolidine et al.</p> |
申请人 |
BANYU PHARMACEUTICAL CO.,LTD.;FUJIMURA, TAKASHI;KISHINO, HIROYUKI;MIZUTANI, TAKASHI;SAKURABA, SHUNJI;SASAKI, TAKAHIDE;SATO, NAGAAKI |
发明人 |
FUJIMURA, TAKASHI;KISHINO, HIROYUKI;MIZUTANI, TAKASHI;SAKURABA, SHUNJI;SASAKI, TAKAHIDE;SATO, NAGAAKI |