| 摘要 |
PROBLEM TO BE SOLVED: To provide a method for producing a fluorine F-18 labeled compound which can integrate, as an efficient operation on a microchip, the synthesis of the fluorine F-18 labeled compound of a multi-stage synthesis process including an evaporation operation. SOLUTION: By using a microchip 1 having gas phase channels 14 in the inside and pooling zones 16 for storing a liquid phase at the bottom of the gas phase channels 14, a solution including a fluorine F-18 ion is introduced into the microchip 1 as the liquid phase. By utilizing the capillary force, the solution including a fluorine F-18 ion is dispersed into the pooling zones 16 of the microchip 1. The gas phase is run into the gas phase channels 14 to evaporate the solution including the fluorine F-18 ion stored in the pooling zones 16 to dryness. Since the evaporation operation with high efficiency can be achieved within the microchip 1, the synthetic process of a fluorine F-18 labeled compound including an evaporation operation such as evaporation to dryness or solvent distilling-away operation can be integrated on the microchip 1 with high efficiency. COPYRIGHT: (C)2011,JPO&INPIT |
