发明名称 7-Azaindole Derivatives as Selective 11-Beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitors
摘要 The present invention relates to 7-azaindole derivatives of formula I as selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11&bgr;-HSD-1) and the use of such compounds for the treatment and prevention of metabolic syndrome, diabetes, insulin resistance, obesity, lipid disorders, glaucoma, osteoporosis, cognitive disorders, anxiety, depression, immune disorders, hypertension and other diseases and conditions.
申请公布号 US2010267761(A1) 申请公布日期 2010.10.21
申请号 US20080741254 申请日期 2008.10.01
申请人 MERCK PATENT GESELLSCHAFT 发明人 CARNIATO DENIS;ROCHE DIDIER;HALLAKOU-BOZEC SOPHIE;SCHULTZ MELANIE
分类号 A61K31/437;A61P3/04;A61P3/06;A61P3/10;A61P9/10;A61P9/12;A61P25/22;A61P25/24;A61P25/28;A61P27/06;C07D471/04 主分类号 A61K31/437
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