发明名称 SOLUBLE INHIBITORS OF VASCULAR ENDOTHELIAL GROWTH FACTOR AND USE THEREOF
摘要 The present invention relates to cDNA encoding a soluble neuropilin protein (sNP) which is isolated from neuropilin (NP) producing cells or is recombinantly engineered from NP-encoding DNA. NP-1 and NP-2 are preferred NPs but any neuropilin or VEGF receptor (VEGFR), where the constituents share at least about 85% homology with either of the above VEGF165R/NP-1 and NP-2. More preferably, such constituent shares at least 90% homology. Still more preferably, each constituent shares at least 95% homology.
申请公布号 US2010267140(A1) 申请公布日期 2010.10.21
申请号 US20100756737 申请日期 2010.04.08
申请人 CHILDREN'S MEDICAL CENTER CORPORATION 发明人 KLAGSBRUN MICHAEL;SOKER SHAY;GAGNON MICHAEL L.
分类号 C12N15/09;C12N15/12;A61K38/00;A61K48/00;A61P19/02;A61P27/02;A61P29/00;A61P35/00;A61P35/04;A61P43/00;C07K14/71;C12N1/15;C12N1/19;C12N1/21;C12N5/09;C12N5/10;C12N15/85 主分类号 C12N15/09
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