发明名称 |
SMAC MIMETIC COMPOUNDS AS APOPTOSIS INDUCERS |
摘要 |
The present invention relates to compounds conformationally constrained mimetics of Smac with function as inhibitors of Inhibitor of Apoptosis Proteins (IAPs), the invention also relates to the use of these compounds in therapy, wherein the induction of apoptotic cell death is beneficial, especially in the treatment of cancer, alone or in combination with other active ingredients.
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申请公布号 |
US2010267692(A1) |
申请公布日期 |
2010.10.21 |
申请号 |
US20080741862 |
申请日期 |
2008.11.05 |
申请人 |
SCOLASTICO CARLO;MANZONI LEONARDO PIERPAOLO;SENECI PIERFAUSTO;BELVISI LAURA;DELIA DOMENICO;BOLOGNESI MARTINO;MASTRANGELO ELOISE;MILANI MARIO;MOTTO ILARIA;DRAGO CARMELO |
发明人 |
SCOLASTICO CARLO;MANZONI LEONARDO PIERPAOLO;SENECI PIERFAUSTO;BELVISI LAURA;DELIA DOMENICO;BOLOGNESI MARTINO;MASTRANGELO ELOISE;MILANI MARIO;MOTTO ILARIA;DRAGO CARMELO |
分类号 |
A61K31/55;A61P35/00;C07D487/04;C07D487/14 |
主分类号 |
A61K31/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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