发明名称 |
IMIDAZOPYRAZINES FOR USE AS KINASE INHIBITORS |
摘要 |
<p>There is provided compounds of formula (I), wherein R1, R2, R3, R4 and R5 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PI3-K and/or mTOR) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.</p> |
申请公布号 |
WO2010119264(A1) |
申请公布日期 |
2010.10.21 |
申请号 |
WO2010GB00773 |
申请日期 |
2010.04.16 |
申请人 |
CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO);PASTOR FERNANDEZ, JOAQUIN;MARTINEZ GONZALEZ, SONIA;OYARZABAL SANTAMARINA, JULEN |
发明人 |
PASTOR FERNANDEZ, JOAQUIN;MARTINEZ GONZALEZ, SONIA;OYARZABAL SANTAMARINA, JULEN |
分类号 |
C07D487/04;A61K31/4985;A61P35/00;A61P37/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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