| 发明名称 |
FUSED PYRROLOPYRIDINE DERIVATIVE |
| 摘要 |
Disclosed is a fused pyrrolopyridine derivative which is useful as an active ingredient for a pharmaceutical composition, in particular a pharmaceutical composition for prevention or treatment of diseases that are caused by undesirable cytokine signaling or diseases that are caused by abnormal cytokine signaling. The inventors have intensively studied on compounds having JAK inhibitory activity, and found that the compound of the present invention, namely a fused pyrrolopyridine derivative has excellent JAK inhibitory activity and is thus useful as an agent for prevention or treatment of diseases that are caused by undesirable cytokine signaling or diseases that are caused by abnormal cytokine signaling.
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| 申请公布号 |
CA2758359(A1) |
申请公布日期 |
2010.10.21 |
| 申请号 |
CA20102758359 |
申请日期 |
2010.04.13 |
| 申请人 |
ASTELLAS PHARMA INC. |
发明人 |
SHIRAKAMI, SHOHEI;NAKAJIMA, YUTAKA;MAEDA, JUN;TOMINAGA, HIROAKI;YAMAGISHI, HIROAKI;HONDO, TAKESHI;INAMI, MASAMICHI;MORIO, HIROKI;INOUE, TAKAYUKI;MIZUTANI, TSUYOSHI;ISHIOKA, HIROKI |
| 分类号 |
C07D471/14;A61K31/437;A61K31/439;A61K31/4545;A61K31/497;A61K31/541;A61K31/55;A61P1/04;A61P1/16;A61P3/10;A61P7/00;A61P9/00;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P17/02;A61P17/04;A61P17/06;A61P17/08;A61P17/10;A61P17/14;A61P19/02;A61P21/04;A61P25/00;A61P25/06;A61P25/28;A61P27/02;A61P29/00;A61P35/00;A61P35/02;A61P37/00;A61P37/06;A61P43/00;C07D519/00 |
主分类号 |
C07D471/14 |
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