The invention relates to modified HPV particles that can be used therapeutically. Modified HPV particles may be used to deliver therapeutic agents, including siRNA molecules. Modified HPV particles may be used for the treatment of diseases or conditions of mucosal tissue, including HPV (human papilloma virus) infection and HPV-related tumors.
申请公布号
CA2795906(A1)
申请公布日期
2010.10.21
申请号
CA20092795906
申请日期
2009.07.24
申请人
INSERM, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;AURA BIOSCIENCES, INC.
发明人
COURSAGET, PIERRE L.;TOUZE, ANTOINE A.;FLEURY, MAXIME J. J.;COMBELAS, NICOLAS;DE LOS PINOS, ELISABET